Of the 9.4 million Americans who take opioids for long term pain, 2.1 million are estimated by National Institute of Health to be addicted to them. On average, 46 Americans die every day from prescription – opioid overdose. The US has the highest rate of opioid use in the world.
Over 20% of all Emergency Department visits involving alcohol and other drugs were related to benzodiazepines. 1
Various medications classes such as antidepressants, antipsychotics, analgesics, and oncologic can be ineffective for 20-75% of treated patients. 2
Almost 40% of ADRs in Medicare patients were classified as serious, life threatening, or fatal with CNS, cardiology and analgesic medications among top ten cited in ADRs. 3